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	<title>Transcriptional repression therapeutics &#8211; BIOENGINEER.ORG</title>
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		<title>Stopping Huntington’s Disease by Targeting CAG Repeats</title>
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		<pubDate>Sat, 15 Nov 2025 01:18:40 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[CAG repeat stabilization]]></category>
		<category><![CDATA[Huntington's disease treatment]]></category>
		<category><![CDATA[Repeat expansion disorders]]></category>
		<category><![CDATA[Somatic instability reduction]]></category>
		<category><![CDATA[Transcriptional repression therapeutics]]></category>
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					<description><![CDATA[In an extraordinary leap forward in the understanding of Huntington’s disease, a new study published in Nature Communications unveils revolutionary strategies to suppress somatic instability in the disorder by targeting the genetic sequences themselves. Huntington’s disease, a devastating neurodegenerative condition, is caused by the expansion of CAG trinucleotide repeats in the HTT gene, which progressively [&#8230;]]]></description>
		
		
		
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