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	<title>time in therapeutic range &#8211; BIOENGINEER.ORG</title>
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		<title>Warfarin Exposure, Not Standard Monitoring, Tracks Brain Small Vessel Damage in Elderly Stroke Patients</title>
		<link>https://bioengineer.org/warfarin-exposure-not-standard-monitoring-tracks-brain-small-vessel-damage-in-elderly-stroke-patients/</link>
		
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		<pubDate>Tue, 27 Oct 2026 07:32:11 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Atrial Fibrillation]]></category>
		<category><![CDATA[cerebral small vessel disease]]></category>
		<category><![CDATA[cognitive impairment]]></category>
		<category><![CDATA[Elderly Patients]]></category>
		<category><![CDATA[INR variability]]></category>
		<category><![CDATA[ischemic stroke]]></category>
		<category><![CDATA[Pharmacokinetics]]></category>
		<category><![CDATA[population pharmacokinetic-pharmacodynamic modeling]]></category>
		<category><![CDATA[time in therapeutic range]]></category>
		<category><![CDATA[vascular dementia]]></category>
		<category><![CDATA[warfarin]]></category>
		<category><![CDATA[white matter hyperintensities]]></category>
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					<description><![CDATA[A retrospective cohort study of 300 elderly stroke patients with atrial fibrillation found that model-estimated warfarin exposure, rather than conventional time in therapeutic range, was associated with cerebral small vessel disease burden and cognitive impairment.]]></description>
		
		
		
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