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	<title>Th1 response &#8211; BIOENGINEER.ORG</title>
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		<title>When Oxygen Runs Low: Hypoxia Reshapes IL-12 and IFN-γ as Prognostic Markers in Intracellular Infection</title>
		<link>https://bioengineer.org/when-oxygen-runs-low-hypoxia-reshapes-il-12-and-ifn-%ce%b3-as-prognostic-markers-in-intracellular-infection/</link>
		
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		<pubDate>Fri, 16 Oct 2026 19:51:41 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[cytokine storm]]></category>
		<category><![CDATA[HIF-1α]]></category>
		<category><![CDATA[hypoxia]]></category>
		<category><![CDATA[IFN-γ]]></category>
		<category><![CDATA[IL-12]]></category>
		<category><![CDATA[immune resolution]]></category>
		<category><![CDATA[Mortality Prediction]]></category>
		<category><![CDATA[Mycobacterium tuberculosis]]></category>
		<category><![CDATA[Prognostic biomarkers]]></category>
		<category><![CDATA[rat model]]></category>
		<category><![CDATA[ROC analysis]]></category>
		<category><![CDATA[Th1 response]]></category>
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					<description><![CDATA[A rat model study shows that hypoxia modulates IL-12 and IFN-γ cytokine dynamics during mycobacterial infection, with early IFN-γ levels offering exploratory prognostic thresholds for mortality prediction.]]></description>
		
		
		
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