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	<title>T-cell acute lymphoblastic leukemia &#8211; BIOENGINEER.ORG</title>
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		<title>ZFX Drives T-cell Leukemia Growth Through m5C Methylation of PD1 mRNA</title>
		<link>https://bioengineer.org/zfx-drives-t-cell-leukemia-growth-through-m5c-methylation-of-pd1-mrna/</link>
		
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		<pubDate>Tue, 27 Oct 2026 23:11:08 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[C57BL/6 mouse model]]></category>
		<category><![CDATA[ChIP-qPCR]]></category>
		<category><![CDATA[Jurkat]]></category>
		<category><![CDATA[m5C methylation]]></category>
		<category><![CDATA[MOLT4]]></category>
		<category><![CDATA[mRNA stabilization]]></category>
		<category><![CDATA[NSUN2]]></category>
		<category><![CDATA[PD1]]></category>
		<category><![CDATA[RNA modification]]></category>
		<category><![CDATA[T-cell acute lymphoblastic leukemia]]></category>
		<category><![CDATA[therapeutic targets]]></category>
		<category><![CDATA[ZFX]]></category>
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					<description><![CDATA[A new study shows that ZFX promotes T-cell acute lymphoblastic leukemia by activating NSUN2-mediated m5C methylation, which stabilizes PD1 mRNA.]]></description>
		
		
		
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