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	<title>sperm channel &#8211; BIOENGINEER.ORG</title>
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		<title>Histidine Clusters Reveal How Heat and pH Switch On the Sperm Channel CatSper</title>
		<link>https://bioengineer.org/histidine-clusters-reveal-how-heat-and-ph-switch-on-the-sperm-channel-catsper/</link>
		
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		<pubDate>Sat, 10 Oct 2026 07:54:51 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[AlphaFold3]]></category>
		<category><![CDATA[Calcium signaling]]></category>
		<category><![CDATA[capacitation]]></category>
		<category><![CDATA[CatSper]]></category>
		<category><![CDATA[Comparative genomics]]></category>
		<category><![CDATA[electrophysiology]]></category>
		<category><![CDATA[histidine]]></category>
		<category><![CDATA[Male Fertility]]></category>
		<category><![CDATA[pH sensing]]></category>
		<category><![CDATA[sperm channel]]></category>
		<category><![CDATA[supramolecular assembly]]></category>
		<category><![CDATA[temperature activation]]></category>
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					<description><![CDATA[New research in PLOS Biology shows that evolutionarily tuned histidine clusters on the sperm channel CatSper act as temperature- and pH-sensitive switches that couple neighboring channels into synchronized activation.]]></description>
		
		
		
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