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	<title>single-cell omics integration &#8211; BIOENGINEER.ORG</title>
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		<title>Integrative scATAC-seq and mtDNA Mutation Analysis Uncovers Disease-Driven Regulatory Disruptions in AML</title>
		<link>https://bioengineer.org/integrative-scatac-seq-and-mtdna-mutation-analysis-uncovers-disease-driven-regulatory-disruptions-in-aml/</link>
		
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		<pubDate>Fri, 08 Aug 2025 16:32:42 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[acute myeloid leukemia]]></category>
		<category><![CDATA[Chromatin accessibility]]></category>
		<category><![CDATA[leukemia stem cell dynamics]]></category>
		<category><![CDATA[mtDNA lineage tracing]]></category>
		<category><![CDATA[single-cell omics integration]]></category>
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					<description><![CDATA[In recent advancements within the realm of hematologic malignancies, researchers have shed new light on the intricate regulatory disruptions driving acute myeloid leukemia (AML) development and relapse. AML, a highly aggressive blood cancer characterized by the abnormal proliferation of myeloid precursor cells, remains a formidable clinical challenge largely due to its genetic complexity and frequent [&#8230;]]]></description>
		
		
		
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