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	<title>serum amyloid A &#8211; BIOENGINEER.ORG</title>
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		<title>AI-Designed Enzymes Slice Disease Proteins With Unprecedented Precision</title>
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		<pubDate>Sat, 17 Oct 2026 08:36:18 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Technology]]></category>
		<category><![CDATA[amyloid-beta]]></category>
		<category><![CDATA[David Baker]]></category>
		<category><![CDATA[de novo enzymes]]></category>
		<category><![CDATA[enzymology]]></category>
		<category><![CDATA[Institute for Protein Design]]></category>
		<category><![CDATA[metalloproteases]]></category>
		<category><![CDATA[protease-activatable prodrugs]]></category>
		<category><![CDATA[Protein Design]]></category>
		<category><![CDATA[RFdiffusion]]></category>
		<category><![CDATA[serum amyloid A]]></category>
		<category><![CDATA[TDP-43]]></category>
		<category><![CDATA[zinc catalysis]]></category>
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					<description><![CDATA[Researchers have used AI-driven protein design to create entirely new zinc-dependent proteases that cleave disease-linked proteins such as TDP-43 and amyloid-beta with rate enhancements of up to ten billion fold.]]></description>
		
		
		
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