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		<title>Synthetic bile acid blocks deadly C. difficile toxin</title>
		<link>https://bioengineer.org/synthetic-bile-acid-blocks-deadly-c-difficile-toxin/</link>
		
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		<pubDate>Tue, 18 Nov 2025 14:39:17 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[allosteric inhibition]]></category>
		<category><![CDATA[Clostridioides difficile treatment]]></category>
		<category><![CDATA[cryo-EM drug design** **Kısa açıklama:** 1. **synthetic bile acid therapy:** Çalışmanın ana odağı]]></category>
		<category><![CDATA[İşte içeriğe uygun 5 adet etiket (virgülle ayrılmış): **synthetic bile acid therapy]]></category>
		<category><![CDATA[sentetik safra asidi analoğu (s]]></category>
		<category><![CDATA[toxin B inhibition]]></category>
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					<description><![CDATA[In an era where antimicrobial resistance poses an escalating global health threat, the pursuit of innovative therapeutics against devastating bacterial pathogens is more critical than ever. Among these pathogens, Clostridioides difficile stands out as a notorious cause of severe infectious diarrhea and life-threatening colitis, predominantly affecting hospitalized patients and individuals with disrupted gut microbiota. The [&#8230;]]]></description>
		
		
		
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