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	<title>reverse remodeling &#8211; BIOENGINEER.ORG</title>
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		<title>Sotatercept May Reach Beyond Pulmonary Hypertension Into Heart Failure and Transplant Care</title>
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		<pubDate>Thu, 15 Oct 2026 23:08:35 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[activin signaling]]></category>
		<category><![CDATA[CADENCE trial]]></category>
		<category><![CDATA[heart failure]]></category>
		<category><![CDATA[heart transplantation]]></category>
		<category><![CDATA[HFpEF]]></category>
		<category><![CDATA[left ventricular assist device]]></category>
		<category><![CDATA[Pulmonary arterial hypertension]]></category>
		<category><![CDATA[pulmonary hypertension]]></category>
		<category><![CDATA[pulmonary vascular resistance]]></category>
		<category><![CDATA[reverse remodeling]]></category>
		<category><![CDATA[right ventricular function]]></category>
		<category><![CDATA[sotatercept]]></category>
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					<description><![CDATA[An opinion article argues that the activin-trap drug sotatercept, proven in pulmonary arterial hypertension and supported by the CADENCE trial in heart failure, should now be tested in staged trials across advanced heart failure, LVAD support, and heart transplantation.]]></description>
		
		
		
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