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	<title>Precision oncology biomarkers &#8211; BIOENGINEER.ORG</title>
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		<title>Targeting Mismatch Repair-Deficient Cancers Therapeutically</title>
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		<pubDate>Sat, 26 Jul 2025 13:14:53 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[Genomic instability in oncology]]></category>
		<category><![CDATA[Immune checkpoint inhibitors]]></category>
		<category><![CDATA[Immunotherapy for MSI-H cancers]]></category>
		<category><![CDATA[Mismatch repair deficiency (MMRd)]]></category>
		<category><![CDATA[Precision oncology biomarkers]]></category>
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					<description><![CDATA[The Intricacies and Therapeutic Promise of Mismatch Repair-Deficient Cancers In the ever-evolving landscape of cancer biology, one molecular pathway has captivated researchers due to its pivotal role in maintaining genomic fidelity: DNA mismatch repair (MMR). This intricate system is a molecular sentinel, intrinsically conserved across species, tasked with recognizing and correcting replication errors that inevitably [&#8230;]]]></description>
		
		
		
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