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		<title>Childhood Brain Tumor Study Uncovers KDM2B as a Selective Epigenetic Vulnerability</title>
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				<category><![CDATA[Biology]]></category>
		<category><![CDATA[bivalent enhancer]]></category>
		<category><![CDATA[chromatin states]]></category>
		<category><![CDATA[epigenomics]]></category>
		<category><![CDATA[H3K27me3]]></category>
		<category><![CDATA[KDM2B]]></category>
		<category><![CDATA[medulloblastoma]]></category>
		<category><![CDATA[Neuronal Differentiation]]></category>
		<category><![CDATA[pediatric brain tumor]]></category>
		<category><![CDATA[Polycomb]]></category>
		<category><![CDATA[PRC1]]></category>
		<category><![CDATA[PRC2]]></category>
		<category><![CDATA[targeted protein degradation]]></category>
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					<description><![CDATA[A comprehensive epigenomic map of medulloblastoma reveals that the chromatin regulator KDM2B sustains the highest-risk tumor subgroups by locking neuronal differentiation genes in a poised, repressed state, making it a promising therapeutic target.]]></description>
		
		
		
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