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	<title>PKA inhibition &#8211; BIOENGINEER.ORG</title>
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		<title>Dual-Tagged Nanovesibles Hitch a Ride Across Heart Capillaries to Deliver a One-Two Punch Against Reperfusion Injury</title>
		<link>https://bioengineer.org/dual-tagged-nanovesibles-hitch-a-ride-across-heart-capillaries-to-deliver-a-one-two-punch-against-reperfusion-injury/</link>
		
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		<pubDate>Sat, 24 Oct 2026 12:03:12 +0000</pubDate>
				<category><![CDATA[Technology]]></category>
		<category><![CDATA[cardiac targeting]]></category>
		<category><![CDATA[CD36]]></category>
		<category><![CDATA[Drug delivery]]></category>
		<category><![CDATA[edaravone]]></category>
		<category><![CDATA[heart disease]]></category>
		<category><![CDATA[KOdiA-PC]]></category>
		<category><![CDATA[myocardial ischemia-reperfusion injury]]></category>
		<category><![CDATA[Nanomedicine]]></category>
		<category><![CDATA[PKA inhibition]]></category>
		<category><![CDATA[siRNA delivery]]></category>
		<category><![CDATA[small extracellular vesicles]]></category>
		<category><![CDATA[transendothelial transport]]></category>
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					<description><![CDATA[Researchers engineered small extracellular vesicles with two targeting tags that exploit the heart's fatty acid transport machinery, improving delivery of edaravone and PKA-silencing RNA and reducing cardiac injury in mouse models of ischemia-reperfusion and permanent infarction.]]></description>
		
		
		
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