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	<title>Phosphorothioate-modified ASOs &#8211; BIOENGINEER.ORG</title>
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	<title>Phosphorothioate-modified ASOs &#8211; BIOENGINEER.ORG</title>
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		<title>Profiling Antibodies Targeting Chemical Modifications in Antisense Oligonucleotides</title>
		<link>https://bioengineer.org/profiling-antibodies-targeting-chemical-modifications-in-antisense-oligonucleotides/</link>
		
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		<pubDate>Thu, 31 Jul 2025 16:46:04 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[2′-O-methoxyethyl RNA therapeutics]]></category>
		<category><![CDATA[Antibody tools for ASO tracking]]></category>
		<category><![CDATA[Biodistribution of nucleic acid drugs]]></category>
		<category><![CDATA[Intracellular trafficking studies]]></category>
		<category><![CDATA[Phosphorothioate-modified ASOs]]></category>
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					<description><![CDATA[In a remarkable advancement within the field of nucleic acid therapeutics, researchers have unveiled a new set of antibody tools capable of precisely targeting chemically modified antisense oligonucleotides (ASOs). These innovations promise to revolutionize how scientists track and understand the intracellular trafficking and biodistribution of ASO therapeutics, enabling a deeper understanding of their mechanisms and [&#8230;]]]></description>
		
		
		
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