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	<title>perilipin-3 &#8211; BIOENGINEER.ORG</title>
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		<title>Metabolic Stress Rewires the Golgi, Sphingolipids and Lipid Droplets in Failing Beta Cells</title>
		<link>https://bioengineer.org/metabolic-stress-rewires-the-golgi-sphingolipids-and-lipid-droplets-in-failing-beta-cells/</link>
		
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		<pubDate>Wed, 14 Oct 2026 01:12:18 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[beta-cell dysfunction]]></category>
		<category><![CDATA[ceramide]]></category>
		<category><![CDATA[glucolipotoxicity]]></category>
		<category><![CDATA[Golgi stress]]></category>
		<category><![CDATA[INS-1E cells]]></category>
		<category><![CDATA[insulin processing]]></category>
		<category><![CDATA[lipid droplets]]></category>
		<category><![CDATA[palmitic acid]]></category>
		<category><![CDATA[PC1/3]]></category>
		<category><![CDATA[perilipin-3]]></category>
		<category><![CDATA[sphingolipid metabolism]]></category>
		<category><![CDATA[Type 2 diabetes]]></category>
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					<description><![CDATA[A new study shows that metabolic stress in insulin-producing beta cells simultaneously remodels Golgi stress proteins, sphingolipid metabolism and lipid droplet regulation, revealing an integrated early molecular signature of beta-cell vulnerability in type 2 diabetes.]]></description>
		
		
		
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