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	<title>paraquat-induced &#8211; BIOENGINEER.ORG</title>
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		<title>Disulfiram Shows Kidney-Protective Effects Against Paraquat Poisoning in Rat Study</title>
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		<pubDate>Sun, 25 Oct 2026 14:19:11 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[animal study]]></category>
		<category><![CDATA[attenuates]]></category>
		<category><![CDATA[disulfiram]]></category>
		<category><![CDATA[Drug repurposing]]></category>
		<category><![CDATA[Fibrosis]]></category>
		<category><![CDATA[nephrology]]></category>
		<category><![CDATA[oxidative stress]]></category>
		<category><![CDATA[paraquat]]></category>
		<category><![CDATA[paraquat-induced]]></category>
		<category><![CDATA[renal]]></category>
		<category><![CDATA[TGF-beta signaling]]></category>
		<category><![CDATA[Toxicology]]></category>
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					<description><![CDATA[In a rat model of paraquat-induced kidney damage, the approved drug disulfiram reduced tissue injury, fibrosis, and oxidative stress, with changes in Smad3 and Smad7 gene expression pointing toward the TGF-beta signaling pathway.]]></description>
		
		
		
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