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	<title>oxygen-induced retinopathy &#8211; BIOENGINEER.ORG</title>
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		<title>Chemokine Signal Behind VEGF-Driven Retinal Neovascularization Identified</title>
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		<pubDate>Sun, 25 Oct 2026 09:43:31 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[ATF6]]></category>
		<category><![CDATA[CXCL1]]></category>
		<category><![CDATA[CXCL2]]></category>
		<category><![CDATA[CXCR2]]></category>
		<category><![CDATA[diabetic retinopathy]]></category>
		<category><![CDATA[GRP78]]></category>
		<category><![CDATA[IL-8]]></category>
		<category><![CDATA[oxygen-induced retinopathy]]></category>
		<category><![CDATA[retinal neovascularization]]></category>
		<category><![CDATA[VEGFA]]></category>
		<category><![CDATA[VEGFR2]]></category>
		<category><![CDATA[VEGFR3]]></category>
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					<description><![CDATA[A new study shows that VEGF-driven retinal neovascularization depends on a VEGFR2-VEGFR3-ATF6-GRP78 signaling axis that induces the chemokines CXCL1/2 and IL-8 and their receptor CXCR2, which blocking antibodies suppress in mouse and human retinal endothelial cells and in a mouse model of pathological retinal angiogenesis.]]></description>
		
		
		
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