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		<title>NU7441 shows dual BRD4 and DNA-PK activity in ovarian cancer cells</title>
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		<pubDate>Mon, 26 Oct 2026 22:52:12 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[acetylated chromatin]]></category>
		<category><![CDATA[BRD4]]></category>
		<category><![CDATA[convergence]]></category>
		<category><![CDATA[DNA Repair]]></category>
		<category><![CDATA[DNA-PK]]></category>
		<category><![CDATA[drug discovery]]></category>
		<category><![CDATA[NU7441]]></category>
		<category><![CDATA[Ovarian cancer]]></category>
		<category><![CDATA[preclinical research]]></category>
		<category><![CDATA[reveals]]></category>
		<category><![CDATA[Therapeutic]]></category>
		<category><![CDATA[vulnerability]]></category>
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					<description><![CDATA[Preclinical assays found that NU7441 displaced BRD4 from acetylated chromatin and impaired homologous recombination and non-homologous end joining in ovarian cancer models.]]></description>
		
		
		
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