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	<title>NRF2/HO-1 signaling in cancer &#8211; BIOENGINEER.ORG</title>
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	<title>NRF2/HO-1 signaling in cancer &#8211; BIOENGINEER.ORG</title>
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		<title>Nelfinavir Induces Ferroptosis via ER Stress in Liver Cancer</title>
		<link>https://bioengineer.org/nelfinavir-induces-ferroptosis-via-er-stress-in-liver-cancer/</link>
		
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		<pubDate>Wed, 08 Oct 2025 08:54:44 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[ER stress mechanisms in HCC]]></category>
		<category><![CDATA[GPX4/GSH system regulation]]></category>
		<category><![CDATA[mitochondrial dysfunction in liver cancer]]></category>
		<category><![CDATA[Nelfinavir-induced ferroptosis]]></category>
		<category><![CDATA[NRF2/HO-1 signaling in cancer]]></category>
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					<description><![CDATA[In a groundbreaking development in cancer research, scientists have uncovered a novel mechanism by which the antiviral drug Nelfinavir induces ferroptosis—an iron-dependent form of regulated cell death—in hepatocellular carcinoma (HCC) cells. This discovery not only broadens our understanding of ferroptosis regulation but also opens promising therapeutic avenues for liver cancer, a malignancy notoriously resistant to [&#8230;]]]></description>
		
		
		
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