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		<title>Ancient Microbe&#8217;s Nitrogenase Caught in Action by Cryo-EM Reveals a Giant Off-Switch Supercomplex</title>
		<link>https://bioengineer.org/ancient-microbes-nitrogenase-caught-in-action-by-cryo-em-reveals-a-giant-off-switch-supercomplex/</link>
		
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		<pubDate>Wed, 07 Oct 2026 18:27:54 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Technology]]></category>
		<category><![CDATA[2-oxoglutarate]]></category>
		<category><![CDATA[archaea]]></category>
		<category><![CDATA[Cryo-EM]]></category>
		<category><![CDATA[enzyme regulation]]></category>
		<category><![CDATA[metalloenzyme]]></category>
		<category><![CDATA[methanogen]]></category>
		<category><![CDATA[Methanosarcina acetivorans]]></category>
		<category><![CDATA[NifDK]]></category>
		<category><![CDATA[NifI]]></category>
		<category><![CDATA[nitrogen fixation]]></category>
		<category><![CDATA[nitrogenase]]></category>
		<category><![CDATA[PII proteins]]></category>
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					<description><![CDATA[The first cryo-EM structure of a native archaeal nitrogenase reveals a giant PII-bridged supercomplex that locks the enzyme inactive until cellular energy and nitrogen signals release it.]]></description>
		
		
		
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