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	<title>neuroinflammation regulation &#8211; BIOENGINEER.ORG</title>
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		<title>Astrocytic PKM2 Deletion Impacts Neuronal Death Post-TBI</title>
		<link>https://bioengineer.org/astrocytic-pkm2-deletion-impacts-neuronal-death-post-tbi/</link>
		
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		<pubDate>Tue, 11 Nov 2025 14:59:10 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Astrocytic PKM2 deletion]]></category>
		<category><![CDATA[Metabolic coupling in TBI]]></category>
		<category><![CDATA[neuroinflammation regulation]]></category>
		<category><![CDATA[Neuronal survival mechanisms]]></category>
		<category><![CDATA[Neuroprotective strategies]]></category>
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					<description><![CDATA[In a groundbreaking study poised to reshape our understanding of traumatic brain injury (TBI), researchers have unveiled the pivotal role of the enzyme pyruvate kinase M2 (PKM2) within astrocytes and its profound influence on neuronal survival post-injury. This pioneering work elucidates cellular mechanisms that could forge new neuroprotective strategies, potentially transforming therapeutic approaches for millions [&#8230;]]]></description>
		
		
		
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		<title>GAS6/AXL Boosts M2 Microglia to Ease Sepsis Brain Inflammation</title>
		<link>https://bioengineer.org/gas6-axl-boosts-m2-microglia-to-ease-sepsis-brain-inflammation/</link>
		
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		<pubDate>Fri, 06 Jun 2025 07:16:41 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Efferocytosis in neuroinflammation]]></category>
		<category><![CDATA[GAS6/AXL signaling pathway]]></category>
		<category><![CDATA[M2 microglia efferocytosis]]></category>
		<category><![CDATA[M2 microglia function]]></category>
		<category><![CDATA[neuroinflammation regulation]]></category>
		<category><![CDATA[Sepsis-associated encephalopathy]]></category>
		<category><![CDATA[therapeutic targets for neuroprotection]]></category>
		<category><![CDATA[Therapeutic targets for sepsis]]></category>
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					<description><![CDATA[In a groundbreaking study published in Cell Death Discovery, researchers have unveiled new insights into the molecular mechanisms that regulate neuroinflammation in sepsis-associated encephalopathy (SAE), a severe and often fatal complication of sepsis affecting the brain. The study highlights the pivotal role of the GAS6/AXL signaling pathway in promoting the efferocytosis function of M2 microglia, [&#8230;]]]></description>
		
		
		
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