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	<title>neointimal hyperplasia &#8211; BIOENGINEER.ORG</title>
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		<title>DDIT4 protein worsens artery narrowing by disrupting smooth muscle cell metabolism</title>
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		<pubDate>Mon, 26 Oct 2026 18:17:28 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Atherosclerosis]]></category>
		<category><![CDATA[DDIT4]]></category>
		<category><![CDATA[epigenetics]]></category>
		<category><![CDATA[histone acetylation]]></category>
		<category><![CDATA[metabolism]]></category>
		<category><![CDATA[muscle]]></category>
		<category><![CDATA[neointimal hyperplasia]]></category>
		<category><![CDATA[phenotypic switching]]></category>
		<category><![CDATA[pyruvate dehydrogenase complex]]></category>
		<category><![CDATA[restenosis]]></category>
		<category><![CDATA[Smooth]]></category>
		<category><![CDATA[vascular smooth muscle cells]]></category>
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					<description><![CDATA[A Nature Communications study shows that the protein DDIT4 drives vascular smooth muscle cell switching and artery thickening in mice and humans by impairing pyruvate dehydrogenase complex activity and reducing histone acetylation at contractile genes.]]></description>
		
		
		
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