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	<title>mutant huntingtin &#8211; BIOENGINEER.ORG</title>
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		<title>Hidden Protein Networks Emerge as Central Players in Huntington&#8217;s Disease</title>
		<link>https://bioengineer.org/hidden-protein-networks-emerge-as-central-players-in-huntingtons-disease/</link>
		
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		<pubDate>Tue, 06 Oct 2026 21:35:25 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[autophagy]]></category>
		<category><![CDATA[Gene Therapy]]></category>
		<category><![CDATA[Huntington’s disease]]></category>
		<category><![CDATA[Mitochondrial dysfunction]]></category>
		<category><![CDATA[mutant huntingtin]]></category>
		<category><![CDATA[Neuroinflammation]]></category>
		<category><![CDATA[NLRP3 inflammasome]]></category>
		<category><![CDATA[protein-protein interaction networks]]></category>
		<category><![CDATA[proteostasis]]></category>
		<category><![CDATA[synaptic dysfunction]]></category>
		<category><![CDATA[TFEB]]></category>
		<category><![CDATA[ubiquitin-proteasome system]]></category>
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					<description><![CDATA[A new review argues that Huntington's disease is driven by widespread disruptions of interconnected protein networks, pointing to hub proteins such as HSP70, DRP1, NLRP3 and TFEB as promising therapeutic targets.]]></description>
		
		
		
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