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	<title>mTREX2 &#8211; BIOENGINEER.ORG</title>
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		<title>Exonuclease Boost Makes CRISPR Cas12a Cut Big Chunks Out of Sugarcane&#8217;s Daunting Genome</title>
		<link>https://bioengineer.org/exonuclease-boost-makes-crispr-cas12a-cut-big-chunks-out-of-sugarcanes-daunting-genome/</link>
		
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		<pubDate>Mon, 12 Oct 2026 17:42:59 +0000</pubDate>
				<category><![CDATA[Agriculture]]></category>
		<category><![CDATA[biofuel feedstock]]></category>
		<category><![CDATA[capillary electrophoresis]]></category>
		<category><![CDATA[cis-regulatory elements]]></category>
		<category><![CDATA[CRISPR-Cas12a]]></category>
		<category><![CDATA[Genome editing]]></category>
		<category><![CDATA[large deletions]]></category>
		<category><![CDATA[LbCas12a-RRV]]></category>
		<category><![CDATA[lw1 gene]]></category>
		<category><![CDATA[mTREX2]]></category>
		<category><![CDATA[Plant biotechnology]]></category>
		<category><![CDATA[polyploid genome]]></category>
		<category><![CDATA[sugarcane]]></category>
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					<description><![CDATA[Researchers report the first CRISPR/Cas12a editing of sugarcane, showing that co-expressing the mTREX2 exonuclease boosts large deletions seven-fold and enables efficient multiallelic editing of the lw1 gene in the crop's highly polyploid genome.]]></description>
		
		
		
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