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		<title>Astrocytes Drive the Mitochondrial Traffic Jams Behind a Common Form of ALS</title>
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		<pubDate>Fri, 09 Oct 2026 04:48:55 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[amyotrophic lateral sclerosis]]></category>
		<category><![CDATA[Astrocytes]]></category>
		<category><![CDATA[axonal transport]]></category>
		<category><![CDATA[C9ORF72]]></category>
		<category><![CDATA[CRISPR gene correction]]></category>
		<category><![CDATA[induced pluripotent stem cells]]></category>
		<category><![CDATA[live-cell imaging]]></category>
		<category><![CDATA[mitochondrial bioenergetics]]></category>
		<category><![CDATA[mitochondrial transport]]></category>
		<category><![CDATA[motor neurons]]></category>
		<category><![CDATA[non-cell-autonomous neurodegeneration]]></category>
		<category><![CDATA[PGC-1α]]></category>
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					<description><![CDATA[New research shows that astrocytes carrying the C9ORF72 mutation disrupt mitochondrial transport in motor neurons through a contact-dependent bioenergetic mechanism that can be reversed by boosting the glial metabolic regulator PGC-1α.]]></description>
		
		
		
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