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		<title>Water&#8217;s Hidden Shape Reveals the Trigger Point That Spreads Dementia Proteins</title>
		<link>https://bioengineer.org/waters-hidden-shape-reveals-the-trigger-point-that-spreads-dementia-proteins/</link>
		
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		<pubDate>Mon, 12 Oct 2026 21:19:53 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Alzheimer's disease]]></category>
		<category><![CDATA[drug target]]></category>
		<category><![CDATA[fibrils]]></category>
		<category><![CDATA[frontotemporal dementia]]></category>
		<category><![CDATA[misfolding]]></category>
		<category><![CDATA[molecular recognition]]></category>
		<category><![CDATA[neurodegeneration]]></category>
		<category><![CDATA[Northwestern University]]></category>
		<category><![CDATA[PNAS]]></category>
		<category><![CDATA[protein aggregation]]></category>
		<category><![CDATA[tau protein]]></category>
		<category><![CDATA[water structuring]]></category>
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					<description><![CDATA[Northwestern University researchers have identified a single water-defined hotspot on tau proteins that drives the misfolding cascade behind Alzheimer's and frontotemporal dementia, offering a precise new target for drugs and diagnostics.]]></description>
		
		
		
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