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	<title>microtubules &#8211; BIOENGINEER.ORG</title>
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		<title>Chemotherapy drug taxol reshapes microtubules to switch on a key cell signal</title>
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		<pubDate>Thu, 08 Oct 2026 20:16:14 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[actin cytoskeleton]]></category>
		<category><![CDATA[cell signalling]]></category>
		<category><![CDATA[chemotherapy]]></category>
		<category><![CDATA[Cryo-EM]]></category>
		<category><![CDATA[discodermolide]]></category>
		<category><![CDATA[GEF-H1]]></category>
		<category><![CDATA[lattice conformation]]></category>
		<category><![CDATA[microtubules]]></category>
		<category><![CDATA[paclitaxel]]></category>
		<category><![CDATA[RhoA]]></category>
		<category><![CDATA[taxanes]]></category>
		<category><![CDATA[tubulin code]]></category>
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					<description><![CDATA[New research shows that taxane chemotherapy drugs expand the microtubule lattice and thereby release the signalling protein GEF-H1, rapidly activating RhoA-dependent actin remodelling in cells.]]></description>
		
		
		
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