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	<title>Metastasis prevention &#8211; BIOENGINEER.ORG</title>
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		<title>Dual IGF-1R and Autophagy Block Halts Cancer Spread</title>
		<link>https://bioengineer.org/dual-igf-1r-and-autophagy-block-halts-cancer-spread/</link>
		
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		<pubDate>Fri, 26 Dec 2025 11:51:47 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[autophagy blockade]]></category>
		<category><![CDATA[cancer cell survival mechanisms]]></category>
		<category><![CDATA[colorectal cancer metastasis]]></category>
		<category><![CDATA[combination therapy]]></category>
		<category><![CDATA[IGF-1R inhibition]]></category>
		<category><![CDATA[Metastasis prevention]]></category>
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					<description><![CDATA[In a groundbreaking advance poised to reshape the therapeutic landscape of colorectal cancer, researchers Mahgoub, Bajbouj, Ahmed, and colleagues have elucidated a novel combinatorial strategy that effectively prevents metastasis. Published in Medical Oncology in 2026, this study reveals how simultaneous inhibition of the insulin growth factor 1 receptor (IGF-1R) and autophagy pathways can stymie the [&#8230;]]]></description>
		
		
		
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