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	<title>metabolic reprogramming of cancer &#8211; BIOENGINEER.ORG</title>
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		<title>SMIM4 Regulates Redox via Malate in Pancreatic Cancer</title>
		<link>https://bioengineer.org/smim4-regulates-redox-via-malate-in-pancreatic-cancer/</link>
		
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		<pubDate>Wed, 05 Nov 2025 15:00:11 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[malate compartmentalization mechanism]]></category>
		<category><![CDATA[metabolic reprogramming of cancer]]></category>
		<category><![CDATA[redox balance in cancer cells]]></category>
		<category><![CDATA[SMIM4 role in pancreatic cancer]]></category>
		<category><![CDATA[therapeutic targets in pancreatic cancer]]></category>
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					<description><![CDATA[In a groundbreaking study published in Nature Communications, researchers have unveiled a pivotal role of the integral membrane protein SMIM4 in modulating redox balance within pancreatic cancer cells. This discovery sheds light on the complex metabolic orchestration that underpins the aggressive nature of pancreatic tumors and opens promising avenues for therapeutic intervention aimed at disrupting [&#8230;]]]></description>
		
		
		
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