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	<title>metabolic maturation &#8211; BIOENGINEER.ORG</title>
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		<title>Stem Cells Reveal a Hidden Lipid Code That Drives Human Heart Cell Maturation</title>
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		<pubDate>Sun, 11 Oct 2026 19:42:24 +0000</pubDate>
				<category><![CDATA[Technology]]></category>
		<category><![CDATA[ATAC-seq]]></category>
		<category><![CDATA[cardiac differentiation]]></category>
		<category><![CDATA[cardiolipin]]></category>
		<category><![CDATA[cardiomyocytes]]></category>
		<category><![CDATA[heart regeneration]]></category>
		<category><![CDATA[human embryonic stem cells]]></category>
		<category><![CDATA[Lipidomics]]></category>
		<category><![CDATA[metabolic maturation]]></category>
		<category><![CDATA[multi-omics]]></category>
		<category><![CDATA[phosphatidylcholine]]></category>
		<category><![CDATA[polyunsaturated lipids]]></category>
		<category><![CDATA[Sphingolipids]]></category>
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					<description><![CDATA[A multi-omics study has mapped stage-specific lipid remodeling across human stem cell differentiation into cardiomyocytes, revealing that polyunsaturated phospholipids accumulate as cells mature and that phosphatidylcholine supplementation modulates maturation and hypertrophy gene programs.]]></description>
		
		
		
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