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	<title>Max &#8211; BIOENGINEER.ORG</title>
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		<title>Virtual screening yields two drug candidates that disable c-Myc in colorectal cancer</title>
		<link>https://bioengineer.org/virtual-screening-yields-two-drug-candidates-that-disable-c-myc-in-colorectal-cancer/</link>
		
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		<pubDate>Fri, 23 Oct 2026 12:49:28 +0000</pubDate>
				<category><![CDATA[Chemistry]]></category>
		<category><![CDATA[ADME]]></category>
		<category><![CDATA[Apoptosis]]></category>
		<category><![CDATA[c-MYC]]></category>
		<category><![CDATA[Colorectal cancer]]></category>
		<category><![CDATA[drug discovery]]></category>
		<category><![CDATA[in vitro]]></category>
		<category><![CDATA[Max]]></category>
		<category><![CDATA[MM/GBSA]]></category>
		<category><![CDATA[molecular docking]]></category>
		<category><![CDATA[molecular dynamics]]></category>
		<category><![CDATA[protein-protein interaction]]></category>
		<category><![CDATA[virtual screening]]></category>
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					<description><![CDATA[A multi-stage virtual screening campaign against the c-Myc/Max dimerization interface has identified two small molecules that suppress c-Myc protein, block its transcriptional activity, and kill colorectal cancer cells with preliminary in-vitro selectivity.]]></description>
		
		
		
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