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	<title>Leigh Syndrome genetics &#8211; BIOENGINEER.ORG</title>
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		<title>New NDUFA3 Variants Linked to Mitochondrial Disorder</title>
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		<pubDate>Fri, 03 Oct 2025 06:50:59 +0000</pubDate>
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		<category><![CDATA[Complex I deficiencies]]></category>
		<category><![CDATA[Leigh Syndrome genetics]]></category>
		<category><![CDATA[mitochondrial disease research]]></category>
		<category><![CDATA[mitochondrial respiratory chain dysfunction]]></category>
		<category><![CDATA[NDUFA3 gene variants]]></category>
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					<description><![CDATA[Mitochondrial disorders represent a complex and multifaceted group of diseases rooted in the dysfunction of the mitochondrial respiratory chain (RC), an essential biochemical apparatus responsible for cellular energy production. Within this complex system, various protein complexes orchestrate the electron transport necessary for ATP synthesis. Among these complexes, Complex I (CI) stands as the largest and [&#8230;]]]></description>
		
		
		
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