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	<title>Knoevenagel condensation &#8211; BIOENGINEER.ORG</title>
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	<title>Knoevenagel condensation &#8211; BIOENGINEER.ORG</title>
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		<title>Fluorinated Alcohol Solvent Drives Catalyst-Free Pyran Synthesis in Minutes</title>
		<link>https://bioengineer.org/fluorinated-alcohol-solvent-drives-catalyst-free-pyran-synthesis-in-minutes/</link>
		
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		<pubDate>Sat, 10 Oct 2026 14:50:27 +0000</pubDate>
				<category><![CDATA[Chemistry]]></category>
		<category><![CDATA[catalyst-free synthesis]]></category>
		<category><![CDATA[fluorinated solvents]]></category>
		<category><![CDATA[Green chemistry]]></category>
		<category><![CDATA[heterocyclic chemistry]]></category>
		<category><![CDATA[HFIP]]></category>
		<category><![CDATA[hydrogen bonding]]></category>
		<category><![CDATA[Knoevenagel condensation]]></category>
		<category><![CDATA[Michael addition]]></category>
		<category><![CDATA[multicomponent reaction]]></category>
		<category><![CDATA[organic synthesis]]></category>
		<category><![CDATA[pyran synthesis]]></category>
		<category><![CDATA[tetrahydrobenzo[b]pyrans]]></category>
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					<description><![CDATA[Chemists report that the fluorinated solvent HFIP alone can promote a one-pot, catalyst-free synthesis of biologically important pyran derivatives in high yields within minutes at 55 degrees Celsius.]]></description>
		
		
		
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