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	<title>isoallolithocholic acid &#8211; BIOENGINEER.ORG</title>
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		<title>Gut Microbe Bile Acid Isoallo-LCA Eases Acute Liver Transplant Rejection in Mice via NR4A1/FOXP3 Pathway</title>
		<link>https://bioengineer.org/gut-microbe-bile-acid-isoallo-lca-eases-acute-liver-transplant-rejection-in-mice-via-nr4a1-foxp3-pathway/</link>
		
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		<pubDate>Tue, 27 Oct 2026 06:20:34 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[acute allograft rejection]]></category>
		<category><![CDATA[bile acid metabolites]]></category>
		<category><![CDATA[FOXP3]]></category>
		<category><![CDATA[gut microbiota]]></category>
		<category><![CDATA[immune tolerance]]></category>
		<category><![CDATA[immunosuppression]]></category>
		<category><![CDATA[isoallolithocholic acid]]></category>
		<category><![CDATA[liver transplantation]]></category>
		<category><![CDATA[NR4A1]]></category>
		<category><![CDATA[orthotopic liver transplantation]]></category>
		<category><![CDATA[regulatory T cells]]></category>
		<category><![CDATA[Th1 cells]]></category>
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					<description><![CDATA[A gut microbial bile acid, isoallolithocholic acid, prolonged survival and reduced rejection injury in a mouse liver transplant model by activating the NR4A1/FOXP3 signaling axis to shift intrahepatic Th1/Treg balance toward tolerance.]]></description>
		
		
		
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