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	<title>integrase strand transfer inhibitor &#8211; BIOENGINEER.ORG</title>
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		<title>Integrase Inhibitors Suppress HIV Faster but Bring Metabolic Trade-offs in Real-World Chinese Cohort</title>
		<link>https://bioengineer.org/integrase-inhibitors-suppress-hiv-faster-but-bring-metabolic-trade-offs-in-real-world-chinese-cohort/</link>
		
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		<pubDate>Mon, 19 Oct 2026 07:22:29 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[antiretroviral therapy]]></category>
		<category><![CDATA[China]]></category>
		<category><![CDATA[effectiveness]]></category>
		<category><![CDATA[Hiv]]></category>
		<category><![CDATA[integrase strand transfer inhibitor]]></category>
		<category><![CDATA[laboratory]]></category>
		<category><![CDATA[metabolic]]></category>
		<category><![CDATA[metabolic outcomes]]></category>
		<category><![CDATA[Outcome]]></category>
		<category><![CDATA[Real-world evidence]]></category>
		<category><![CDATA[virological]]></category>
		<category><![CDATA[virological suppression]]></category>
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					<description><![CDATA[A province-wide cohort study of 7,474 treatment-naïve adults in Shandong, China finds INSTI-based initial HIV therapy outperforms NNRTI-based regimens on virological suppression and high-level viremia, but carries higher risks of weight gain, cholesterol elevation, bilirubin rise, and early kidney function decline within the first year of routine care.]]></description>
		
		
		
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