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	<title>immunotherapy resistance mechanisms &#8211; BIOENGINEER.ORG</title>
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		<title>New Insights into Immunotherapy Failure Offer New Hope for Cancer Patients</title>
		<link>https://bioengineer.org/new-insights-into-immunotherapy-failure-offer-new-hope-for-cancer-patients/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Wed, 17 Sep 2025 18:15:50 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[bexmarilimab cancer therapy]]></category>
		<category><![CDATA[immunotherapy resistance mechanisms]]></category>
		<category><![CDATA[Precision oncology advancements]]></category>
		<category><![CDATA[secreted Clever-1 protein]]></category>
		<category><![CDATA[T cell activation suppression]]></category>
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					<description><![CDATA[A groundbreaking study led by researchers at the University of Birmingham, in collaboration with the University of Turku in Finland, has unveiled a pivotal mechanism behind the failure of immunotherapy in numerous cancer patients. Supported by the National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre, this investigation sheds light on a [&#8230;]]]></description>
		
		
		
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		<title>Targeting the Interaction of Key Proteins: A New Avenue for Cancer Therapy</title>
		<link>https://bioengineer.org/targeting-the-interaction-of-key-proteins-a-new-avenue-for-cancer-therapy/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Wed, 14 May 2025 21:16:56 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[Cancer immunotherapy]]></category>
		<category><![CDATA[cancer therapy resistance]]></category>
		<category><![CDATA[dendritic cell maturation]]></category>
		<category><![CDATA[dendritic cell-mediated immunity]]></category>
		<category><![CDATA[immunotherapy resistance mechanisms]]></category>
		<category><![CDATA[STAT3 degraders in oncology]]></category>
		<category><![CDATA[STAT3-STAT5 interaction]]></category>
		<category><![CDATA[STAT3-STAT5 signaling balance]]></category>
		<category><![CDATA[targeted protein degradation]]></category>
		<category><![CDATA[targeted protein degradation therapy]]></category>
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					<description><![CDATA[Immunotherapy has revolutionized cancer treatment by harnessing the body’s own immune system to identify and eradicate malignant cells. Among the various strategies employed, immune checkpoint inhibitors have shown promise by disrupting the molecular brakes that tumors impose upon immune cells, effectively unleashing a more potent anti-cancer response. These therapies work by blocking specific proteins that [&#8230;]]]></description>
		
		
		
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