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	<title>Immunotherapy biomarkers &#8211; BIOENGINEER.ORG</title>
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		<title>PD-1 Inhibition in Pancreatic Cancer: Testing Insights</title>
		<link>https://bioengineer.org/pd-1-inhibition-in-pancreatic-cancer-testing-insights/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Tue, 21 Oct 2025 22:53:33 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[Immunotherapy biomarkers]]></category>
		<category><![CDATA[MMRd vs MSS PDAC]]></category>
		<category><![CDATA[Pancreatic ductal adenocarcinoma]]></category>
		<category><![CDATA[PD-1 inhibition]]></category>
		<category><![CDATA[personalized oncology strategies]]></category>
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					<description><![CDATA[Recent advancements in oncology have unveiled a pressing need to explore the intricacies of immune checkpoint inhibitors, particularly focusing on PD-1 inhibition in specific cancer types. One such focus has emerged in the context of pancreatic ductal adenocarcinoma (PDAC), a formidable adversary due to its aggressive nature and dismal prognosis. A pivotal study spearheaded by [&#8230;]]]></description>
		
		
		
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		<title>Craters on Melanoma Cell Surfaces Identified as Key Sites for Tumor Destruction</title>
		<link>https://bioengineer.org/craters-on-melanoma-cell-surfaces-identified-as-key-sites-for-tumor-destruction/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Fri, 17 Oct 2025 15:16:03 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[CD8+ T cell engagement]]></category>
		<category><![CDATA[CD8+ T cells]]></category>
		<category><![CDATA[CRATER tumor niches]]></category>
		<category><![CDATA[CRATERs]]></category>
		<category><![CDATA[Immunotherapy biomarkers]]></category>
		<category><![CDATA[tumor microenvironment]]></category>
		<category><![CDATA[Zebrafish melanoma model]]></category>
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					<description><![CDATA[Recent groundbreaking research published in the prestigious journal Cell reveals a fascinating and previously uncharted feature on the surface of melanoma cells: immune “craters.” These crater-like structures serve as specialized hubs that significantly enhance the engagement between tumor cells and CD8+ T cells, a critical component of the immune system’s arsenal against cancer. This discovery [&#8230;]]]></description>
		
		
		
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