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	<title>immune dysregulation &#8211; BIOENGINEER.ORG</title>
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		<title>Male Bias in Placental Alterations of Late-Onset Preeclampsia</title>
		<link>https://bioengineer.org/male-bias-in-placental-alterations-of-late-onset-preeclampsia/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Wed, 24 Dec 2025 16:38:52 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Fetal sex differences]]></category>
		<category><![CDATA[immune dysregulation]]></category>
		<category><![CDATA[Late-onset preeclampsia]]></category>
		<category><![CDATA[maternal-fetal health]]></category>
		<category><![CDATA[Placental transcriptome]]></category>
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					<description><![CDATA[In a groundbreaking study poised to transform our understanding of preeclampsia, researchers have identified significant sex-specific differences in placental transcriptomes, particularly in the context of late-onset preeclampsia. This research, published in the journal Biological Sex Differences, sheds light on the unique biological pathways influenced by the male and female fetal environments, marking a pivotal moment [&#8230;]]]></description>
		
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">310974</post-id>	</item>
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		<title>Male-Biased Immune Changes in Late-Onset Preeclampsia</title>
		<link>https://bioengineer.org/male-biased-immune-changes-in-late-onset-preeclampsia/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Wed, 24 Dec 2025 15:30:35 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[başlıkta ve içerikte vurgulanıyor. 2. **Placental transcriptomics]]></category>
		<category><![CDATA[immune dysregulation]]></category>
		<category><![CDATA[İşte bu içerik için 5 uygun etiket (virgülle ayrılmış): **Late-onset preeclampsia]]></category>
		<category><![CDATA[Metabolic dysregulation** **Açıklama:** 1. **Late-onset preeclampsia:** Makalenin temel konusu]]></category>
		<category><![CDATA[Placental transcriptomics]]></category>
		<category><![CDATA[sex differences]]></category>
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					<description><![CDATA[Recent research has unveiled critical insights into the complex relationship between placental transcriptomics and the pathophysiology of late-onset preeclampsia, a condition that predominantly affects pregnant women in their later trimesters. The study, led by a team of notable researchers including Smith, M.D., Plaisier, S., and Breen, J., sheds light on the sex-specific differences observed in [&#8230;]]]></description>
		
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">310947</post-id>	</item>
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		<title>cDC3s Impair Anti-TNF-α Therapy in Ulcerative Colitis</title>
		<link>https://bioengineer.org/cdc3s-impair-anti-tnf-%ce%b1-therapy-in-ulcerative-colitis/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Mon, 06 Oct 2025 05:36:38 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[anti-TNF-α therapy]]></category>
		<category><![CDATA[cDC3s]]></category>
		<category><![CDATA[immune dysregulation]]></category>
		<category><![CDATA[single-cell RNA sequencing]]></category>
		<category><![CDATA[ulcerative colitis]]></category>
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					<description><![CDATA[In a groundbreaking study published in the Journal of Translational Medicine, researchers have unveiled significant insights into the role of different immune cell populations in ulcerative colitis (UC) and their response to anti-tumor necrosis factor-alpha (anti-TNF-α) therapy. The study conducted by Li, Ma, Nie, and their team leverages cutting-edge single-cell RNA sequencing technology to elucidate [&#8230;]]]></description>
		
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">276154</post-id>	</item>
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		<title>X-Linked Transcriptome Disruption in Lupus Immune Cells</title>
		<link>https://bioengineer.org/x-linked-transcriptome-disruption-in-lupus-immune-cells/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Thu, 25 Sep 2025 17:31:32 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[gender disparities in autoimmunity]]></category>
		<category><![CDATA[immune dysregulation]]></category>
		<category><![CDATA[systemic lupus erythematosus]]></category>
		<category><![CDATA[transcriptomic immune cell profiles]]></category>
		<category><![CDATA[X-linked transcriptome disruption]]></category>
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					<description><![CDATA[In a groundbreaking study published in the esteemed journal Biology of Sex Differences, researchers have unveiled critical insights into the complex interplay of genetics and immune responses in systemic lupus erythematosus (SLE), an autoimmune condition predominantly affecting women. The research, led by Miguel Soares, I.S. Wemans, and P. Caldas, focuses on the dysregulation of the [&#8230;]]]></description>
		
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">272313</post-id>	</item>
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		<title>Groundbreaking Study Shows Rheumatoid Arthritis Develops Years Before Symptoms, Paving the Way for Preventive Strategies</title>
		<link>https://bioengineer.org/groundbreaking-study-shows-rheumatoid-arthritis-develops-years-before-symptoms-paving-the-way-for-preventive-strategies/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Wed, 24 Sep 2025 18:48:27 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Autoimmune disease mechanisms]]></category>
		<category><![CDATA[B cell-T cell interaction in autoimmunity]]></category>
		<category><![CDATA[early autoimmune biomarkers]]></category>
		<category><![CDATA[immune dysregulation]]></category>
		<category><![CDATA[preclinical rheumatoid arthritis]]></category>
		<category><![CDATA[preventive immunology strategies]]></category>
		<category><![CDATA[Preventive strategies]]></category>
		<category><![CDATA[Rheumatoid arthritis early detection]]></category>
		<category><![CDATA[systemic immune dysregulation]]></category>
		<category><![CDATA[Systemic inflammation]]></category>
		<guid isPermaLink="false">https://bioengineer.org/groundbreaking-study-shows-rheumatoid-arthritis-develops-years-before-symptoms-paving-the-way-for-preventive-strategies/</guid>

					<description><![CDATA[In a groundbreaking multi-institutional study, researchers have uncovered that the onset of rheumatoid arthritis (RA), a chronic autoimmune disorder characterized by joint inflammation and degradation, begins silently and systemically years before clinical symptoms manifest. This paradigm-shifting research delivers unprecedented insights into the preclinical phase of RA, revealing that immune dysregulation and systemic inflammation set the [&#8230;]]]></description>
		
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">271879</post-id>	</item>
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		<title>Transcriptomics Reveal Immune Dysfunctions in VEXAS Syndrome</title>
		<link>https://bioengineer.org/transcriptomics-reveal-immune-dysfunctions-in-vexas-syndrome/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Tue, 20 May 2025 17:19:17 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[autoinflammatory disorders]]></category>
		<category><![CDATA[immune dysregulation]]></category>
		<category><![CDATA[transcriptomic profiling]]></category>
		<category><![CDATA[UBA1 gene mutations]]></category>
		<category><![CDATA[VEXAS syndrome]]></category>
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					<description><![CDATA[In recent years, the medical community has grappled with understanding the complexities of VEXAS syndrome, a recently characterized autoinflammatory disorder predominantly affecting adult males. Despite its identification only a few years ago, VEXAS has confounded clinicians with its heterogeneous presentation and rapidly progressive course. A groundbreaking study published in Nature Communications by Mizumaki, Gao, Wu, [&#8230;]]]></description>
		
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">245959</post-id>	</item>
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		<title>Single-Cell Insights Reveal Microscopic Colitis Details</title>
		<link>https://bioengineer.org/single-cell-insights-reveal-microscopic-colitis-details/</link>
		
		<dc:creator><![CDATA[Bioengineer]]></dc:creator>
		<pubDate>Sun, 18 May 2025 10:19:38 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[cellular heterogeneity]]></category>
		<category><![CDATA[immune dysregulation]]></category>
		<category><![CDATA[microscopic colitis]]></category>
		<category><![CDATA[single-cell transcriptomics]]></category>
		<category><![CDATA[therapeutic targets]]></category>
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					<description><![CDATA[In a groundbreaking study poised to revolutionize our understanding of gastrointestinal disorders, researchers have employed cutting-edge single-cell transcriptomic technologies to unravel the molecular underpinnings of microscopic colitis—a condition that has long puzzled clinicians due to its subtle histological presentation and elusive pathogenesis. Published in Nature Communications, this comprehensive single-cell profiling marks a significant leap forward [&#8230;]]]></description>
		
		
		
		<post-id xmlns="com-wordpress:feed-additions:1">245664</post-id>	</item>
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