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	<title>hypoxia-induced GPX4 degradation &#8211; BIOENGINEER.ORG</title>
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	<title>hypoxia-induced GPX4 degradation &#8211; BIOENGINEER.ORG</title>
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		<title>Lymph Node Drives FSP1 Target in Melanoma</title>
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		<pubDate>Wed, 05 Nov 2025 21:13:24 +0000</pubDate>
				<category><![CDATA[Technology]]></category>
		<category><![CDATA[ferroptosis regulation in melanoma]]></category>
		<category><![CDATA[FSP1 therapeutic targeting]]></category>
		<category><![CDATA[hypoxia-induced GPX4 degradation]]></category>
		<category><![CDATA[lymph node microenvironment]]></category>
		<category><![CDATA[ubiquitin-proteasome system in cancer]]></category>
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					<description><![CDATA[Recent groundbreaking research has illuminated the critical role of oxygen levels in modulating the vulnerability of melanoma cells to ferroptosis, unveiling new therapeutic targets for metastatic cancer treatment. Investigators have delved into the complex biochemical landscape of the lymph node microenvironment—characterized by notably low free iron, increased oleic acid concentrations, and hypoxia—to decipher how these [&#8230;]]]></description>
		
		
		
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