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		<title>Tiny Pores or Total Rupture: How Lysosome Damage Decides Whether Cells Die by Apoptosis or Necrosis</title>
		<link>https://bioengineer.org/tiny-pores-or-total-rupture-how-lysosome-damage-decides-whether-cells-die-by-apoptosis-or-necrosis/</link>
		
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		<pubDate>Sat, 17 Oct 2026 12:22:51 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[4-hydroxy-2-nonenal]]></category>
		<category><![CDATA[Apoptosis]]></category>
		<category><![CDATA[calpain]]></category>
		<category><![CDATA[cathepsins]]></category>
		<category><![CDATA[Cell Death]]></category>
		<category><![CDATA[ferroptosis]]></category>
		<category><![CDATA[Hsp70.1]]></category>
		<category><![CDATA[lysosomal membrane permeabilization]]></category>
		<category><![CDATA[lysosomal membrane rupture]]></category>
		<category><![CDATA[lysosome]]></category>
		<category><![CDATA[necrosis]]></category>
		<category><![CDATA[pyroptosis]]></category>
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					<description><![CDATA[A new review argues that lysosomal membrane permeabilization and lysosomal membrane rupture are mechanistically distinct failures that determine whether cells die by apoptosis or necrosis, with implications for stroke, Alzheimer's disease and fatty liver injury.]]></description>
		
		
		
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