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	<title>horizontal pleiotropy &#8211; BIOENGINEER.ORG</title>
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		<title>New Genetic Tool Separates Real Causal Effects from Statistical Noise in Disease Studies</title>
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		<pubDate>Thu, 15 Oct 2026 21:14:06 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[appendicular lean mass]]></category>
		<category><![CDATA[Causal Inference]]></category>
		<category><![CDATA[Cholesterol]]></category>
		<category><![CDATA[Genetic epidemiology]]></category>
		<category><![CDATA[Genetic Variants]]></category>
		<category><![CDATA[horizontal pleiotropy]]></category>
		<category><![CDATA[instrumental variables]]></category>
		<category><![CDATA[LDL cholesterol]]></category>
		<category><![CDATA[Mendelian randomization]]></category>
		<category><![CDATA[mixture model]]></category>
		<category><![CDATA[mouse experiments]]></category>
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					<description><![CDATA[Researchers have developed MRZ, a new Mendelian randomization method that robustly classifies genetic instruments to deliver accurate causal estimates, validated by mouse experiments showing muscle mass lowers cholesterol.]]></description>
		
		
		
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