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	<title>hematopoiesis &#8211; BIOENGINEER.ORG</title>
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		<title>Binary Trees for Cell Fates: New Algorithm Reshapes Single-Cell Trajectory Inference</title>
		<link>https://bioengineer.org/binary-trees-for-cell-fates-new-algorithm-reshapes-single-cell-trajectory-inference/</link>
		
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		<pubDate>Tue, 06 Oct 2026 11:47:59 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[cell fate decisions]]></category>
		<category><![CDATA[computational biology]]></category>
		<category><![CDATA[CoSpar]]></category>
		<category><![CDATA[discrete optimization]]></category>
		<category><![CDATA[hematopoiesis]]></category>
		<category><![CDATA[integer programming]]></category>
		<category><![CDATA[minimum spanning tree]]></category>
		<category><![CDATA[pseudotime]]></category>
		<category><![CDATA[single-cell RNA-seq]]></category>
		<category><![CDATA[Slingshot]]></category>
		<category><![CDATA[trajectory inference]]></category>
		<category><![CDATA[Waddington's epigenetic landscape]]></category>
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					<description><![CDATA[Researchers in Hong Kong and Japan have developed an integer programming method that constrains single-cell trajectory trees to binary branching, aligning inferred cell fate hierarchies with Waddington's epigenetic landscape.]]></description>
		
		
		
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