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		<title>AI-designed molecular glue degrader ISM9546 targets VAV1 for autoimmune disease treatment</title>
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		<pubDate>Sun, 18 Oct 2026 06:52:11 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[AI-driven]]></category>
		<category><![CDATA[autoimmune]]></category>
		<category><![CDATA[degrader]]></category>
		<category><![CDATA[glue]]></category>
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		<category><![CDATA[Insilico]]></category>
		<category><![CDATA[ISM9546]]></category>
		<category><![CDATA[molecular]]></category>
		<category><![CDATA[nominates]]></category>
		<category><![CDATA[Oral]]></category>
		<category><![CDATA[peripheral-restricted]]></category>
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					<description><![CDATA[The nomination of ISM9546 arrives at a moment when the field of targeted protein degradation is moving well beyond its original scope. Molecular glue degraders, unlike the more widely known PROTAC molecules, are typically small compounds that induce or stabilize]]></description>
		
		
		
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