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	<title>gene transcription &#8211; BIOENGINEER.ORG</title>
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		<title>Review Links Acute GVHD Steroid Refractoriness to Multiple Molecular Mechanisms</title>
		<link>https://bioengineer.org/review-links-acute-gvhd-steroid-refractoriness-to-multiple-molecular-mechanisms/</link>
		
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		<pubDate>Wed, 21 Oct 2026 08:00:17 +0000</pubDate>
				<category><![CDATA[Biology]]></category>
		<category><![CDATA[acute graft-versus-host disease]]></category>
		<category><![CDATA[allogeneic stem cell transplantation]]></category>
		<category><![CDATA[epigenetic regulation]]></category>
		<category><![CDATA[gene transcription]]></category>
		<category><![CDATA[glucocorticoid receptor]]></category>
		<category><![CDATA[GRα]]></category>
		<category><![CDATA[GRβ]]></category>
		<category><![CDATA[pathogenesis]]></category>
		<category><![CDATA[refractoriness]]></category>
		<category><![CDATA[steroid]]></category>
		<category><![CDATA[steroid refractoriness]]></category>
		<category><![CDATA[Treatment resistance]]></category>
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					<description><![CDATA[A review proposes that steroid refractoriness in acute graft-versus-host disease may arise from multiple abnormalities affecting receptor activation, nuclear translocation, DNA binding, gene transcription, and epigenetic regulation.]]></description>
		
		
		
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