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		<title>Zipalertinib plus chemotherapy extends survival in EGFR exon 20 lung cancer</title>
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		<pubDate>Sun, 25 Oct 2026 11:15:34 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[brain metastases]]></category>
		<category><![CDATA[EGFR exon 20 insertion]]></category>
		<category><![CDATA[first-line treatment]]></category>
		<category><![CDATA[IASLC WCLC 2026]]></category>
		<category><![CDATA[non-small cell lung cancer]]></category>
		<category><![CDATA[objective response rate]]></category>
		<category><![CDATA[phase 3 trial]]></category>
		<category><![CDATA[platinum-pemetrexed chemotherapy]]></category>
		<category><![CDATA[progression-free survival]]></category>
		<category><![CDATA[REZILIENT 3]]></category>
		<category><![CDATA[targeted therapy]]></category>
		<category><![CDATA[zipalertinib]]></category>
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					<description><![CDATA[In the phase 3 REZILIENT 3 trial, adding zipalertinib to platinum-pemetrexed chemotherapy extended median progression-free survival from 8.5 to 14.5 months as first-line treatment for advanced NSCLC with EGFR exon 20 insertion mutations.]]></description>
		
		
		
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