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		<title>Organ-on-Chip Meets Digital Twin: Systematic Review Maps the Future of Drug Development</title>
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		<pubDate>Fri, 16 Oct 2026 18:49:18 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[digital twin]]></category>
		<category><![CDATA[Drug development]]></category>
		<category><![CDATA[drug-induced liver injury]]></category>
		<category><![CDATA[FDA Modernization Act 2.0]]></category>
		<category><![CDATA[IVIVE]]></category>
		<category><![CDATA[Machine Learning]]></category>
		<category><![CDATA[microphysiological systems]]></category>
		<category><![CDATA[organ-on-chip]]></category>
		<category><![CDATA[PBPK modeling]]></category>
		<category><![CDATA[Pharmacokinetics]]></category>
		<category><![CDATA[preclinical testing]]></category>
		<category><![CDATA[systematic review]]></category>
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					<description><![CDATA[A new systematic review of 123 studies shows that pairing organ-on-chip devices with digital twin computational models is rapidly maturing into a validated, regulator-friendly alternative to animal testing in drug development, though only liver applications are truly established.]]></description>
		
		
		
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