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	<title>existential suffering &#8211; BIOENGINEER.ORG</title>
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		<title>Palliative Sedation Often Follows a Cascade of Refractory Symptoms, Not a Single One</title>
		<link>https://bioengineer.org/palliative-sedation-often-follows-a-cascade-of-refractory-symptoms-not-a-single-one/</link>
		
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		<pubDate>Tue, 27 Oct 2026 07:00:27 +0000</pubDate>
				<category><![CDATA[Cancer]]></category>
		<category><![CDATA[advanced cancer]]></category>
		<category><![CDATA[delirium]]></category>
		<category><![CDATA[dyspnoea]]></category>
		<category><![CDATA[end-of-life care]]></category>
		<category><![CDATA[ESAS]]></category>
		<category><![CDATA[existential suffering]]></category>
		<category><![CDATA[midazolam]]></category>
		<category><![CDATA[Observational study]]></category>
		<category><![CDATA[Palliative care]]></category>
		<category><![CDATA[palliative sedation]]></category>
		<category><![CDATA[refractory symptoms]]></category>
		<category><![CDATA[symptom clusters]]></category>
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					<description><![CDATA[An international observational study of 80 advanced cancer patients finds that palliative sedation is typically prompted by multiple interacting refractory symptoms rather than one dominant one, with medication strategies converging rapidly after sedation begins.]]></description>
		
		
		
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