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	<title>Erk MAP kinase &#8211; BIOENGINEER.ORG</title>
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		<title>How Infection Signals Push Kidney Filter Cells Into Leaks, Damage, and Cell Death</title>
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		<pubDate>Mon, 19 Oct 2026 16:07:26 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Apoptosis]]></category>
		<category><![CDATA[Erk MAP kinase]]></category>
		<category><![CDATA[kidney filtration barrier]]></category>
		<category><![CDATA[lipopolysaccharide]]></category>
		<category><![CDATA[metalloproteinases]]></category>
		<category><![CDATA[nephrin]]></category>
		<category><![CDATA[NFκB]]></category>
		<category><![CDATA[podocytes]]></category>
		<category><![CDATA[Proteinuria]]></category>
		<category><![CDATA[reactive oxygen species]]></category>
		<category><![CDATA[slit diaphragm]]></category>
		<category><![CDATA[TLR4]]></category>
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					<description><![CDATA[New research shows that sustained activation of the innate immune receptor TLR4 in podocytes triggers a reversible leak in the kidney filtration barrier, shedding of nephrin, and eventually apoptotic cell death through distinct signaling pathways.]]></description>
		
		
		
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