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	<title>Enzymatic assembly line regulation &#8211; BIOENGINEER.ORG</title>
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		<title>Unlocking Bacterial Non-Ribosomal Peptide Thioesterases</title>
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		<pubDate>Tue, 14 Oct 2025 13:14:26 +0000</pubDate>
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		<category><![CDATA[Bacterial non-ribosomal peptide biosynthesis]]></category>
		<category><![CDATA[Enzymatic assembly line regulation]]></category>
		<category><![CDATA[Non-canonical thioesterase functions]]></category>
		<category><![CDATA[Synthetic biology in natural product biosynthesis]]></category>
		<category><![CDATA[Type-I and Type-II thioesterases]]></category>
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					<description><![CDATA[Thioesterases (TEs), characterized by their α/β hydrolase fold, are pivotal enzymes in the intricate processes of polyketide and non-ribosomal peptide biosynthesis. The distinction between Type-I and Type-II thioesterases is essential, as Type-I TEs are integral to multi-modular enzymatic assembly lines, fundamentally shaping the molecular architectures of the compounds produced, while Type-II TEs operate independently, ensuring [&#8230;]]]></description>
		
		
		
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