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	<title>engineered probiotics &#8211; BIOENGINEER.ORG</title>
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		<title>Engineered Probiotic Turns Gut Bacteria Into Living Drug Factories to Shield the Liver From Colitis Damage</title>
		<link>https://bioengineer.org/engineered-probiotic-turns-gut-bacteria-into-living-drug-factories-to-shield-the-liver-from-colitis-damage/</link>
		
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		<pubDate>Sat, 17 Oct 2026 10:18:59 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[colitis]]></category>
		<category><![CDATA[engineered probiotics]]></category>
		<category><![CDATA[gut-liver axis]]></category>
		<category><![CDATA[inflammatory bowel disease]]></category>
		<category><![CDATA[intestinal barrier]]></category>
		<category><![CDATA[Lactobacillus paracasei]]></category>
		<category><![CDATA[live biotherapeutics]]></category>
		<category><![CDATA[liver injury]]></category>
		<category><![CDATA[NAPE-PLD]]></category>
		<category><![CDATA[NLRP3 inflammasome]]></category>
		<category><![CDATA[palmitoylethanolamide]]></category>
		<category><![CDATA[PPAR alpha]]></category>
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					<description><![CDATA[Scientists engineered a probiotic bacterium that produces the anti-inflammatory lipid palmitoylethanolamide directly in the gut, protecting mice with chronic colitis from secondary liver injury through PPAR-alpha-dependent restoration of barrier integrity and suppression of hepatic inflammatory signaling.]]></description>
		
		
		
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