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	<title>EDL muscle &#8211; BIOENGINEER.ORG</title>
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		<title>Alzheimer&#8217;s Mouse Model Shows Sex-Specific Muscle Fatigue Changes Before Cognitive Decline</title>
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		<pubDate>Sun, 25 Oct 2026 02:07:06 +0000</pubDate>
				<category><![CDATA[Health]]></category>
		<category><![CDATA[Alzheimer's disease]]></category>
		<category><![CDATA[amyloid-beta]]></category>
		<category><![CDATA[EDL muscle]]></category>
		<category><![CDATA[hAβ-KI mouse model]]></category>
		<category><![CDATA[muscle fatigue]]></category>
		<category><![CDATA[oxidative phosphorylation]]></category>
		<category><![CDATA[RNA sequencing]]></category>
		<category><![CDATA[sarcopenia]]></category>
		<category><![CDATA[sex differences]]></category>
		<category><![CDATA[skeletal muscle]]></category>
		<category><![CDATA[soleus]]></category>
		<category><![CDATA[sporadic Alzheimer's disease]]></category>
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					<description><![CDATA[In a humanized amyloid beta knock-in mouse model of sporadic Alzheimer's disease, 8-month-old males show faster muscle fatigue while females show fatigue resistance, with both differences vanishing by 15 months and emerging before known cognitive deficits.]]></description>
		
		
		
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